Host Range Conversion of the Murine Sarcoma-leukaemia Complex

The murine leukemia-sarcoma virus complex.

The development of in vitro (tissue culture) assay systems for murine leukemia (MuLV)l" 2 and sarcoma (MSV)3-7 viruses, the demonstration of the defectiveness of the MSV genome,3 and its rescue with various MuLV's7 have brought out certain remarkable similarities between these viruses and those of the avian leukosisRous sarcoma complex.3' 7, 8, "a Subsequent studies of the murine viruses, which...

Host range of Kaposi's sarcoma-associated herpesvirus in cultured cells.

Difficulties in efficiently propagating Kaposi's sarcoma-associated herpesvirus (KSHV) in culture have generated the impression that the virus displays a narrow host range. Here we show that, contrary to expectation, KSHV can establish latent infection in many adherent cell lines, including human and nonhuman cells of epithelial, endothelial, and mesenchymal origin. (Paradoxically, the only lin...

Lysogeny and bacteriophage host range within the Burkholderia cepacia complex.

The Burkholderia cepacia complex comprises a group of nine closely related species that have emerged as life-threatening pulmonary pathogens in immunocompromised patients, particularly individuals with cystic fibrosis or chronic granulomatous disease. Attempts to explain the genomic plasticity, adaptability and virulence of the complex have paid little attention to bacteriophages, particularly ...

Broadbean wilt virus - identification,host range and distribution in the fars province of iran

The "sarcoma-specific" region of Moloney murine sarcoma virus 124.

Labeled, purified 30S RNA from Moloney murine sarcoma virus was annealed to an excess of Moloney murine leukemia virus complementary DNA. Upon treatment of the resulting DNA.RNA hybrids with RNase H followed by sucrose gradient sedimentation, and undigested 18S RNA molecule was recovered. This RNA molecule was shown to represent the "sarcoma-specific" region of the virus. The unintegrated linea...